![cd4 remove vray settings cd4 remove vray settings](https://www.researchgate.net/publication/221811214/figure/tbl2/AS:203040851271681@1425420119166/Summary-of-validation-data-of-alternate-low-cost-assays-of-CD4-T-cell-count_Q320.jpg)
Guidelines Methodology, Process, and StructureĪ systematic search of the US Centers for Disease Control and Prevention (CDC) Research Project Database was conducted to identify randomized controlled trials (RCTs), observational studies with or without comparators, as well as cross-sectional and descriptive studies from January 2002 to July 2013. 12 The International Association of Providers of AIDS Care (IAPAC), through a multidisciplinary panel of international advisors, developed the first comprehensive, evidence-based guidelines for optimizing the HIV care continuum, with an aim to increase HIV testing coverage, linkage to care, treatment coverage, engagement and retention in care, and viral suppression for adults and adolescents (persons aged 10-19 years). Key to these efforts will be to overcome and/or eliminate legal, social, environmental, and structural barriers that prevent PLHIV from accessing and utilizing HIV services. 9, 10 The number of PLHIV who are diagnosed, on ART, and achieving viral suppression reflect 3 distinct points of patient engagement along the HIV care continuum, also referred to as the cascade of care, 11 with viral suppression as the ultimate clinical goal to improve individual PLHIV health outcomes and reduce HIV acquisition and transmission, thus conferring community and public health benefits.Įfforts are needed to optimize the HIV care continuum in order to attain the 90-90-90 targets. 8Īccording to the Joint United Nations Programme on HIV/AIDS (UNAIDS), an estimated 15 million PLHIV were on ART by mid-2015-about 50% of the estimated number of diagnosed PLHIV-and less than 25% of those on ART were virologically suppressed. 8 Modeling suggests that meeting the 90-90-90 targets by 2020 may decrease AIDS incidence, AIDS-related deaths, and new HIV infections by 90% from 2010 levels by 2030.
![cd4 remove vray settings cd4 remove vray settings](https://i.ytimg.com/vi/XDXBWFTLxfg/maxresdefault.jpg)
8 The new targets propose that by 2020, 90% of all people living with HIV (PLHIV) should know their HIV serostatus, 90% of people who know their HIV-positive status should be receiving sustained ART, and 90% of people on ART should achieve sustained viral suppression. The United Nations (UN) has formally embraced TasP as it proposed a new global target for HIV treatment referred to as the 90-90-90 targets. These medical breakthroughs fostered the development of a treatment as prevention (TasP) strategy, 5, 6 whose aim is to provide early access to HIV testing and treatment to prevent progression to AIDS and premature death as well as HIV transmission. 1 Antiretroviral therapy is also highly effective in preventing the sexual, 2 parenteral, 3 and vertical 4 transmission of HIV. Today, a person diagnosed with HIV at the age of 20 years if started promptly on ART is expected to live a normal life span, with a highly preserved quality of life. Modern antiretroviral therapy (ART) has dramatically changed the course of HIV disease.